A pesticide (1,3-Dichloropropene – 1,3-D) had been historically classified as a likely human carcinogen. The registrant, through a series of studies, had determined that the carcinogenic potential of the formulation was due to the carrier and not the active agent. SciPinion assembled a panel of experts in toxicokinetics, genotoxicity, cancer bioassays and cancer weight of evidence to review the literature and weigh in on how 1,3-D should be classified. The panel of experts were in agreement that 1,3-D should be classified as ‘Not Likely to be Carcinogenic to Humans’. US EPA agreed with this assessment and changed their classification of 1,3-D.
- View the EPA decision.
- View the manuscript.
